The first girders will go up tomorrow night and monday. Parts of the interchange will shutdown.
Crews will work overnight hours installing them, however that still means there will be plenty of delays.
Drivers in northeast Wisconsin frequently use Highway 41 and 29.
"The average daily travel is 69,000 cars," says Mark Kantola of the DOT.
"I usually go through this way every other day," says Pamela Pellinen of Green Bay.
But construction has slowed them down a bit lately irritating drivers.
"It's just not fun at all."
More changes are coming crews are installing tub girders as they continue to build the interchange flyovers. That means more closures.
"To do that we need to do that so that cranes can mobilize out and get out to actually lift these girders into place," says US 41 Project Manager Eric Gwidt.
For the next month crews will install the girders and that may cause delays all the way up into the morning rush hour.
"7 o'clock or 8 o'clock at night until six that next morning these roads are going to be closed and you're going to have to detour," says Kantola.
DOT leaders will provide information every morning telling the public where the detours will be.
But more delays mean more problems for Pamela Pellinen.
"It's hard enough to get to work as it is right now and now there's more delays." But once it's all finished.
"This is going to alleviate all that congestion."
So drivers hope it'll be well worth the wait and hassle.
To make sure drivers are aware the DOT will post a road closure alert on the 41 website and on social media the day before.